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An electrolyte panel, also known as a serum electrolyte test or electrolyte blood test, is a blood test that measures the levels of electrolytes in your body. Electrolytes are minerals and salts that help control the amount of fluid in your body, and help your muscles and nerves function properly. An electrolyte imbalance can occur due to a number of conditions, including dehydration, kidney disease, and cardiovascular disease. Some reasons you might need an electrolyte test include: You're taking medications that can affect electrolyte levels, such as diuretics, blood pressure medications, or anti-seizure medications You collapsed while exercising or playing sports You're in the hospital for a heat-related illness A related test, the anion gap blood test, measures whether your electrolytes are out of balance, or if your blood is too acidic or not acidic enough.