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A liver function test, also known as a liver panel, is a blood test that measures the levels of various substances in your blood to determine how well your liver is functioning. Some of the substances that are measured include: Albumin A protein made in the liver. Low levels of albumin may indicate liver disease. Bilirubin A waste product created when your body breaks down old red blood cells. High levels of bilirubin may indicate a blockage in bile flow or a problem with how the liver processes bile. Alkaline phosphatase (ALP) An enzyme found in the liver and bones. ALP levels can increase during pregnancy and growth spurts. Alanine transaminase (ALT) An enzyme that can be released into the bloodstream when the liver is damaged. Aspartate aminotransferase (AST) An enzyme that can be released into the bloodstream when the liver is damaged. Prothrombin time (PT) A measure of how long it takes your blood to clot. Blood that takes a long time to clot may indicate liver disease. A doctor can use the results of a liver function test to determine if there is liver damage and if medications need to be adjusted. If liver damage is suspected, the doctor may order multiple tests over a period of time to monitor how levels change.