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A protein, albumin, and globulin test measures the amount of protein in your blood, and compares the levels of albumin and globulin. This test can help diagnose or monitor a variety of health conditions, including liver and kidney disease, nutritional deficiencies, and immune system disorders. Test What it measures What it can help diagnose Total protein test Total amount of protein in your blood, including albumin and globulin Liver or kidney disease, nutritional deficiencies Albumin-to-globulin (A/G) ratio test Ratio of albumin to globulin in your blood Liver or kidney disease Serum protein electrophoresis Levels of each type of protein in your blood, including globulins Immune system disorders, multiple myeloma, and other conditions You might need this test if you have symptoms like: Swelling in the feet, ankles, legs, and/or abdomen Fatigue Unexplained weight loss Loss of appetite Nausea and vomiting Jaundice (yellowing of the skin or eyes) Blood in the urine A technician will take a blood sample from a vein in your arm, or sometimes with a finger prick. The results should be back in about 12 hours